"It is likely that you are not as familiar with Vitiligo as you think. You should know that this disease affects more than 1% of the global population, which amounts to approximately 85 million people, twice the population of Argentina. Although this number is considerable, there are actually even more people affected. Some individuals have less visible spots and generally do not disclose them, while others live isolated and unwilling to socialize.
Recent medical advances, such as the deciphering of the genome, have allowed researchers to understand the role of amino acids, proteins, and genes in Vitiligo. A specific relationship has been identified: the erroneous exchange of the essential amino acid leucine (LEU), coded by the codon CUU in RNA, for the semi-essential amino acid histidine (HIS), coded by the codon CAU. This error occurs on chromosome 17, on its short arm and in the cytogenetic band 13.2. When the genotype is "A", it manifests as generalized Vitiligo, although it is not always visibly expressed. If you have the "A" genotype, there is a high probability of developing white spots on the skin at some point in your life.
The commercial saliva analysis, like the one offered by 23andMe for about 235 dollars in the United States, reveals ancestral origin and risks of various diseases but does not include the analysis of Vitiligo. To receive this kit outside the United States, like in Argentina, an additional shipment of approximately 67 dollars is required. A specific study for Vitiligo costs around 995 dollars, an amount not always available to everyone. However, it is essential to carry out this analysis to know personal risks.
The corporation AAHHOO, for 397 dollars, offers a service that includes everything from 23andMe plus the evaluation of the risk of Vitiligo. This price covers the shipment of the kit to collect a saliva sample and its return. This promotion will be available until December 31 and could run out earlier depending on demand.
For those who already suffer from Vitiligo, knowing this genetic error is crucial to adjust their treatment and control. For their family members and other people without visible manifestations, this analysis is essential, as there are vaccines and protocols to prevent the expression of the problematic gene. The importance of this study is immense. If you do not have the necessary resources, it is advisable to continue saving, as this analysis is vital and only required once in a lifetime. For those who understand its importance and have saved to invest in significant matters, this analysis is one of the most meaningful options. The seriousness, professionalism, and accuracy of the results and the process are guaranteed. At the end of the study, you will receive a detailed personal report with recommendations based on the findings."